I work in networking and have the need to connect to console ports on a switch using my MacBook Pro with no serial port. I purchased the IO Gear GUC232A which works great and very well built and uses the prolific driver which has been found to be very well supported also another great more updated choice would be the pluggable usb to serial adapter

Recently with the move to OS X Mountain Lion it stopped working and I found through some research that this is what needs to be done to fix it.

Here’s a way to get you PL2303-based Serial-USB adapter working with OS X Lion (10.7). Based on the osx-pl2303 project on github, utilize a kernel extension that works with OS X Lion. You can grab the kext file from the below attachment.

Installing the kext file can be done in a few easy steps:

download and extract the ktext below:

osx-pl2303.kext

cd /path/to/osx-pl2303.kext

cp -R osx-pl2303.kext /System/Library/Extensions/

next you need to fix permissions and execute bits:

cd /System/Library/Extensions


chmod -R 755 osx-pl2303.kext


chown -R root:wheel osx-pl2303.kext
cd /System/Library/Extensions
kextload ./osx-pl2303.kext
kextcache -system-cache

Once done, unplug and replug the dongle and you should be good to go!

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NOTE: If you are having permission issues with any of the above commands, start them with sudo

 

 

Borrowed from – http://mywiseguys.com/topic/2686-usb-to-serial-interface/